MYO7A and CDH23

Number of citations of the paper that reports this interaction (PubMedID 12485990)
153

Data Source:
HPRD (in vitro)

		MYO7A	CDH23
Description		myosin VIIA	cadherin related 23
Image
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cell Cytoplasm Lysosomal Membrane Cytosol Microvillus Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Cell Junction Myosin VII Complex Vesicle Photoreceptor Connecting Cilium Stereocilium Melanosome Synapse Stereocilium Base Upper Tip-link Density	Cell Plasma Membrane Adherens Junction Cell Surface Membrane Integral Component Of Membrane Catenin Complex Stereocilium
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Spectrin Binding Actin-dependent ATPase Activity Identical Protein Binding ADP Binding Protein N-terminus Binding Actin Filament Binding	Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cadherin Binding
	Biological Process	Phagolysosome Assembly Intracellular Protein Transport Actin Filament Organization Lysosome Organization Sensory Organ Development Visual Perception Sensory Perception Of Sound Actin Filament-based Movement Vesicle Transport Along Actin Filament Cellular Protein Localization Eye Photoreceptor Cell Development Mechanoreceptor Differentiation Post-embryonic Animal Organ Morphogenesis Sensory Perception Of Light Stimulus Equilibrioception Pigment Granule Transport Auditory Receptor Cell Stereocilium Organization	Cell Morphogenesis Calcium Ion Transport Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Visual Perception Sensory Perception Of Sound Locomotory Behavior Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Photoreceptor Cell Maintenance Response To Stimulus Sensory Perception Of Light Stimulus Equilibrioception Regulation Of Cytosolic Calcium Ion Concentration Inner Ear Receptor Cell Stereocilium Organization Cell-cell Adhesion
Pathways		The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal dominant Deafness, autosomal recessive	Usher syndrome (US) Deafness, autosomal recessive
GWAS		Lewy body disease ( 25188341) Post bronchodilator FEV1/FVC ratio ( 26634245) Tourette syndrome ( 30818990)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Bipolar disorder (body mass index interaction) ( 24322204) Blood protein levels ( 29875488) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cognitive performance (processing speed) ( 31598132) Decline in glucose metabolism in posterior cingulate cortex ( 29130521) Diffusing capacity of the lung for carbon monoxide traits ( 30049742) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Kidney function decline traits ( 25493955) Monocyte count ( 27863252) Progranulin levels ( 29186428) Selective IgA deficiency ( 27723758) Self-reported risk-taking behaviour ( 30271922) Vitiligo ( 22951725)
Interacting Genes		12 interacting genes: ACTA1 CALM1 CDH23 KEAP1 KHDRBS1 LINC00839 MAP2 MYRIP PRKAR1A USH1C VEZT WHRN	3 interacting genes: CLK1 MYO7A USH1C
Entrez ID		4647	64072
HPRD ID		02043	05699
Ensembl ID		ENSG00000137474	ENSG00000107736
Uniprot IDs		Q13402	A0A087WYR8 A5D6V9 Q6P152 Q8N5B3 Q9H251
PDB IDs		5MV9	2KBR 2KBS 2LSR 5TFM 5VVM 5WJ8
Enriched GO Terms of Interacting Partners?
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