CDH23 and USH1C

Number of citations of the paper that reports this interaction (PubMedID 12485990)
153

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		CDH23	USH1C
Description		cadherin related 23	USH1 protein network component harmonin
Image
GO Annotations	Cellular Component	Cell Plasma Membrane Adherens Junction Cell Surface Membrane Integral Component Of Membrane Catenin Complex Stereocilium	Photoreceptor Outer Segment Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Brush Border Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Apical Part Of Cell Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cadherin Binding	Protein Binding Spectrin Binding Actin Filament Binding
	Biological Process	Cell Morphogenesis Calcium Ion Transport Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Visual Perception Sensory Perception Of Sound Locomotory Behavior Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Photoreceptor Cell Maintenance Response To Stimulus Sensory Perception Of Light Stimulus Equilibrioception Regulation Of Cytosolic Calcium Ion Concentration Inner Ear Receptor Cell Stereocilium Organization Cell-cell Adhesion	G2/M Transition Of Mitotic Cell Cycle Sensory Perception Of Sound Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Length Cellular Protein-containing Complex Assembly Inner Ear Morphogenesis Inner Ear Auditory Receptor Cell Differentiation Photoreceptor Cell Maintenance Retinal Cone Cell Development Sensory Perception Of Light Stimulus Equilibrioception Actin Filament Bundle Assembly Inner Ear Receptor Cell Development Inner Ear Receptor Cell Stereocilium Organization Protein Localization To Microvillus Brush Border Assembly
Pathways
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal recessive	Usher syndrome (US) Deafness, autosomal recessive
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Bipolar disorder (body mass index interaction) ( 24322204) Blood protein levels ( 29875488) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cognitive performance (processing speed) ( 31598132) Decline in glucose metabolism in posterior cingulate cortex ( 29130521) Diffusing capacity of the lung for carbon monoxide traits ( 30049742) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Kidney function decline traits ( 25493955) Monocyte count ( 27863252) Progranulin levels ( 29186428) Selective IgA deficiency ( 27723758) Self-reported risk-taking behaviour ( 30271922) Vitiligo ( 22951725)	Body mass index ( 26426971) Macular thickness ( 30535121) Night sleep phenotypes ( 27126917)
Interacting Genes		3 interacting genes: CLK1 MYO7A USH1C	10 interacting genes: ANKS4B CDH23 CTNNAL1 FBXO7 MIPOL1 MYO7A QKI RAC1 USH1G USHBP1
Entrez ID		64072	10083
HPRD ID		05699	09241
Ensembl ID		ENSG00000107736	ENSG00000006611
Uniprot IDs		A0A087WYR8 A5D6V9 Q6P152 Q8N5B3 Q9H251	A0A0S2Z4U9 A0A0S2Z4V1 Q9Y6N9
PDB IDs		2KBR 2KBS 2LSR 5TFM 5VVM 5WJ8	1X5N 2KBQ 2KBR 2KBS 2LSR 3K1R 5F3X 5MV8 5MV9 5XBF
Enriched GO Terms of Interacting Partners?
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