MAP1A and HTR2A

Number of citations of the paper that reports this interaction (PubMedID 16537434)
17

Data Source:
HPRD (two hybrid)

		MAP1A	HTR2A
Description		microtubule associated protein 1A	5-hydroxytryptamine receptor 2A
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Microtubule Microtubule Associated Complex Axon Dendrite Cell Projection Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Dendritic Branch Synapse Primary Dendrite Dendritic Microtubule Axon Cytoplasm	Cell Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Cell Junction Axon Dendrite Cytoplasmic Vesicle Neuronal Cell Body Dendritic Shaft Cell Body Fiber Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Microtubule Binding Cytoskeletal Adaptor Activity Tubulin Binding Tau Protein Binding	Virus Receptor Activity G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Drug Binding Neurotransmitter Receptor Activity Identical Protein Binding Protein-containing Complex Binding Serotonin Binding 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding
	Biological Process	Microtubule Cytoskeleton Organization Axonogenesis Memory Associative Learning Dendrite Development Regulation Of Microtubule Depolymerization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Synaptic Plasticity Voluntary Musculoskeletal Movement Neuron Cellular Homeostasis Anterograde Axonal Protein Transport Retrograde Axonal Protein Transport Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Cellular Protein Localization Neuron Projection Maintenance Positive Regulation Of Protein Localization To Cell Surface	Temperature Homeostasis Cellular Calcium Ion Homeostasis G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Phospholipase C-activating Serotonin Receptor Signaling Pathway Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Aging Memory Cell Death Positive Regulation Of Cell Proliferation Positive Regulation Of Phosphatidylinositol Biosynthetic Process Regulation Of Dopamine Secretion Phosphatidylinositol 3-kinase Signaling Artery Smooth Muscle Contraction Urinary Bladder Smooth Muscle Contraction Sleep Response To Drug Negative Regulation Of Potassium Ion Transport Positive Regulation Of MAP Kinase Activity Protein Localization To Cytoskeleton Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Glycolytic Process Positive Regulation Of Vasoconstriction Viral Entry Into Host Cell Behavioral Response To Cocaine Positive Regulation Of Peptidyl-tyrosine Phosphorylation Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Synaptic Vesicle Exocytosis
Pathways			Serotonin receptors G alpha (q) signalling events
Drugs		Estramustine	Ziprasidone Methysergide Cabergoline Ropinirole Amitriptyline Olanzapine Clozapine Mirtazapine Loxapine Remoxipride Pramipexole Promazine Cyproheptadine Imipramine Chlorpromazine Chlorpromazine Haloperidol Nortriptyline Amoxapine Fenfluramine Lisuride Cisapride Fluphenazine Trazodone Thioridazine Ergotamine Apomorphine Paroxetine Trimipramine Risperidone Epinastine Propiomazine Minaprine Donepezil Flupentixol Cyclobenzaprine Mesoridazine Maprotiline Ergoloid mesylate Promethazine Tegaserod Doxepin Nefazodone Desipramine Pergolide Bromocriptine Ketamine Quetiapine Aripiprazole Chlorprothixene Clomipramine Paliperidone Yohimbine Methotrimeprazine MMDA Midomafetamine Dimethyltryptamine 4-Bromo-2,5-dimethoxyphenethylamine Acepromazine Molindone Pipotiazine Thioproperazine Thiothixene Zuclopenthixol Aniracetam Fluspirilene Flibanserin Iloperidone HY10275 APD791 Pimavanserin Epicept NP-1 BL-1020 Cariprazine Lumateperone Sertindole Mianserin Asenapine Amisulpride Deramciclane Esmirtazapine Cinitapride Lurasidone Perospirone Amperozide Butriptyline Brexpiprazole Dosulepin Etoperidone Setiptiline Sarpogrelate Ketanserin Nelotanserin Ritanserin Tiapride
Diseases
GWAS		Platelet count ( 27863252) Plateletcrit ( 27863252) Triglycerides ( 24507774 30275531)	Blood protein levels ( 28240269) Cardiac hypertrophy ( 21348951) Parkinson disease and lewy body pathology ( 25663231) Serum 25-Hydroxyvitamin D levels ( 29325163) SjÃ¶gren's syndrome ( 28076899) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		23 interacting genes: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 RHOB SPP1 TUBA4A TUBB UPF2	18 interacting genes: ANKS1B ARF1 ARF6 DLG4 EIF3F GLUL GNA11 GNAI1 GNAQ JAK2 MAP1A MRPL28 NDUFB10 NME3 NTRK3 PON2 PPP5C RPS6KA3
Entrez ID		4130	3356
HPRD ID		02549	01638
Ensembl ID		ENSG00000166963	ENSG00000102468
Uniprot IDs		P78559 Q504X9	P28223
PDB IDs			6A93 6A94
Enriched GO Terms of Interacting Partners?
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