MAG and PLP1

Number of citations of the paper that reports this interaction (PubMedID 12237860)
4

Data Source:
HPRD (in vivo)

		MAG	PLP1
Description		myelin associated glycoprotein	proteolipid protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Paranode Region Of Axon Myelin Sheath Adaxonal Region Myelin Sheath Compact Myelin Schmidt-Lanterman Incisure Membrane Raft Mesaxon	Plasma Membrane Integral Component Of Membrane Myelin Sheath Synapse
	Molecular Function	Signaling Receptor Binding Protein Kinase Binding Carbohydrate Binding Sialic Acid Binding Protein Homodimerization Activity Ganglioside GT1b Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Cell Adhesion Negative Regulation Of Neuron Projection Development Transmission Of Nerve Impulse Central Nervous System Myelination Negative Regulation Of Axon Extension Axon Regeneration Positive Regulation Of Myelination Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Leukocyte Migration Cellular Response To Mechanical Stimulus Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Inflammatory Response Integrin-mediated Signaling Pathway Chemical Synaptic Transmission Axon Ensheathment Glial Cell Differentiation Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Neuron Projection Development Myelination Long-chain Fatty Acid Biosynthetic Process Axon Development
Pathways		Axonal growth inhibition (RHOA activation) Basigin interactions EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases			Hereditary spastic paraplegia (SPG) Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Interacting Genes		18 interacting genes: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R	13 interacting genes: AKT1 BCL2L13 CALR CANX CLN8 CREB3 CREB3L1 GLA ITGAV LMNA MAG MBP PTPRN
Entrez ID		4099	5354
HPRD ID		01160	02321
Ensembl ID		ENSG00000105695	ENSG00000123560
Uniprot IDs		P20916 Q53ES7	A0A0S2Z4D4 A8K9L3 B4DI30 P60201
PDB IDs			2XPG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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