EPCAM and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 16054130)
53

Data Source:
HPRD (in vitro)

		EPCAM	CLDN7
Description		epithelial cell adhesion molecule	claudin 7
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Cell Surface Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Extracellular Exosome	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane
	Molecular Function	Protein Binding Protein-containing Complex Binding Cadherin Binding Involved In Cell-cell Adhesion	Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Ureteric Bud Development Positive Regulation Of Cell Proliferation Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Leukocyte Migration Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Cell Motility Positive Regulation Of Stem Cell Proliferation	Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Positive Regulation Of Cell Motility
Pathways		Cell surface interactions at the vascular wall	Tight junction interactions
Drugs		oportuzumab monatox ING-1
Diseases		Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS		epithelial cell adhesion molecule levels ( 25147954)	Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		2 interacting genes: CLDN7 TSC22D2	7 interacting genes: AQP2 EPCAM GLP1R HGD RHOXF2 SYNE4 TJP1
Entrez ID		4072	1366
HPRD ID		01709	07633
Ensembl ID		ENSG00000119888	ENSG00000181885
Uniprot IDs		P16422	A0A384ME58 F5H496 O95471
PDB IDs		4MZV 6I07
Enriched GO Terms of Interacting Partners?
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