CLDN7 and EPCAM

Number of citations of the paper that reports this interaction (PubMedID 16054130)
53

Data Source:
HPRD (in vitro)

		CLDN7	EPCAM
Description		claudin 7	epithelial cell adhesion molecule
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane	Plasma Membrane Bicellular Tight Junction Cell Surface Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding	Protein Binding Protein-containing Complex Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Positive Regulation Of Cell Motility	Ureteric Bud Development Positive Regulation Of Cell Proliferation Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Leukocyte Migration Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Cell Motility Positive Regulation Of Stem Cell Proliferation
Pathways		Tight junction interactions	Cell surface interactions at the vascular wall
Drugs			oportuzumab monatox ING-1
Diseases			Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS		Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)	epithelial cell adhesion molecule levels ( 25147954)
Interacting Genes		7 interacting genes: AQP2 EPCAM GLP1R HGD RHOXF2 SYNE4 TJP1	2 interacting genes: CLDN7 TSC22D2
Entrez ID		1366	4072
HPRD ID		07633	01709
Ensembl ID		ENSG00000181885	ENSG00000119888
Uniprot IDs		A0A384ME58 F5H496 O95471	P16422
PDB IDs			4MZV 6I07
Enriched GO Terms of Interacting Partners?
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