RHOG and ARHGDIG

Number of citations of the paper that reports this interaction (PubMedID 8939998)
25

Data Source:
HPRD (two hybrid)

		RHOG	ARHGDIG
Description		ras homolog family member G	Rho GDP dissociation inhibitor gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Secretory Granule Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rac GTPase Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Motor Neuron Axon Guidance Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Engulfment Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Kinase B Signaling Cell Chemotaxis Activation Of GTPase Activity Regulation Of Ruffle Assembly Regulation Of Neutrophil Migration Positive Regulation Of Protein Localization To Plasma Membrane	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		GPVI-mediated activation cascade PIP3 activates AKT signaling Rho GTPase cycle Constitutive Signaling by Aberrant PI3K in Cancer RHO GTPases activate KTN1 Neutrophil degranulation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Rho GTPase cycle
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		19 interacting genes: ARHGDIA ARHGDIG DOCK1 ECT2 ELMO1 ELMO2 ELMOD2 IQGAP2 KTN1 MAP3K11 MCF2 MCF2L PLD1 SMAD1 SMAD4 TGFBR1 VAV1 VAV2 VAV3	8 interacting genes: CDC42 CEP170P1 KXD1 RAC1 RHOA RHOB RHOG RHOH
Entrez ID		391	398
HPRD ID		01537	04163
Ensembl ID		ENSG00000177105	ENSG00000242173
Uniprot IDs		P84095 Q6ICQ8	F1T0H7 Q99819
PDB IDs
Enriched GO Terms of Interacting Partners?
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