KLC1 and BNIP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLC1	BNIP2
Description		kinesin light chain 1	BCL2 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle	Nuclear Envelope Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding	Exopolyphosphatase Activity GTPase Activator Activity Calcium Ion Binding Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly	Polyphosphate Catabolic Process Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Muscle Cell Differentiation
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Myogenesis Myogenesis
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)	Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		21 interacting genes: APP BNIP2 CCDC114 CLSTN1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODF1 PCM1 PLEKHM2 SNCA SPAG9 YWHAB	14 interacting genes: ARHGAP1 ARHGAP8 BCL2 BNIPL CDC42 CREB3 FATE1 FGFR1 FRK KLC1 LMNA MYO5B NCBP1 UPK1B
Entrez ID		3831	663
HPRD ID		02489	04481
Ensembl ID		ENSG00000126214	ENSG00000140299
Uniprot IDs		Q07866 Q7RTQ2	J3KN59 Q12982
PDB IDs		3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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