KLC1 and KIF2A

Number of citations of the paper that reports this interaction (PubMedID 17332754)
59

Data Source:
HPRD (in vivo)

		KLC1	KIF2A
Description		kinesin light chain 1	kinesin family member 2A
Image
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Sperm Principal Piece Centriolar Subdistal Appendage
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly	Microtubule Cytoskeleton Organization Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)	Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483)
Interacting Genes		21 interacting genes: APP BNIP2 CCDC114 CLSTN1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODF1 PCM1 PLEKHM2 SNCA SPAG9 YWHAB	10 interacting genes: CASK CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B MRPL53
Entrez ID		3831	3796
HPRD ID		02489	03996
Ensembl ID		ENSG00000126214	ENSG00000068796
Uniprot IDs		Q07866 Q7RTQ2	B0AZS5 O00139
PDB IDs		3NF1 5OJ8	2GRY 6BBN
Enriched GO Terms of Interacting Partners?
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