IRF2 and HMGB1

  • Number of citations of the paper that reports this interaction (PubMedID 11748221)
  • 38
  • Data Source:
  • HPRD (in vitro)

IRF2

HMGB1

Description interferon regulatory factor 2 high mobility group box 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute kidney injury in critical illness ( 27576016)
  • Adverse response to drug ( 30420678)
  • Chronic lymphocytic leukemia ( 28165464)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Lewy body disease ( 25188341)
  • Night sleep phenotypes ( 27126917)
  • Nonsyndromic cleft lip ( 31609978)
Interacting Genes 22 interacting genes: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 HMGB1 HMGN1 IRF1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFKB1 PPP3CB PRKACA RELA SPI1 STAT1 94 interacting genes: ACBD3 AGER AGTRAP AR ATOH1 C1QBP C3 CASP3 CCAR1 CDK1 CEBPB CREBBP CRMP1 CSNK1A1 CTCF CTNNBL1 CUX1 DNM2 DNMT1 EIF1 ENAH EP300 ERF ERG28 FIP1L1 FOXA3 FOXC1 GTF2A1 HES1 HMGA1 HNRNPK HOXB1 HOXB3 HOXC6 HOXD10 HOXD11 HOXD3 HOXD8 HOXD9 HPF1 HR HSPA5 IRF2 KRT7 LRIF1 MECP2 MNT MT2A NCAN NEUROD6 NEXN NFKB1 NR3C1 PCOLCE PGR PLAT PLG POU5F1 PPP2R3A PRKCA PRKDC PSEN1 PTPRZ1 RAD23B RAG1 RASSF4 RB1 RBPJ RELA RFX1 RPL29 RPS12 RPS20 SIX5 SOX18 SPINT1 TAF1 TBP TERF2 TERF2IP TFE3 TGIF1 TLE1 TLE2 TLE5 TLR2 TLR4 TP53 TP73 UBE2I UNC119 ZFP36 ZNF24 ZNF428
Entrez ID 3660 3146
HPRD ID 00962 01228
Ensembl ID ENSG00000168310 ENSG00000189403
Uniprot IDs P14316 A0A024RDR0 P09429
PDB IDs 2LY4 2RTU 2YRQ 6CG0 6CIJ 6CIK 6CIL 6CIM
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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