DUPD1 and ROR1

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		DUPD1	ROR1
Description		dual specificity phosphatase and pro isomerase domain containing 1	receptor tyrosine kinase like orphan receptor 1
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GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex	Stress Fiber Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Axon Receptor Complex Axon Terminus
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Protein Homodimerization Activity	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Wnt-protein Binding Wnt-activated Receptor Activity Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Nervous System Development Sensory Perception Of Sound Positive Regulation Of Neuron Projection Development Astrocyte Development Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Inner Ear Development Anatomical Structure Development Positive Regulation Of NF-kappaB Transcription Factor Activity Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of ERK1 And ERK2 Cascade
Pathways			WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Drugs
Diseases
GWAS		Anxiety disorder ( 25390645) Height ( 31562340)	Blood protein levels ( 30072576 29875488) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Pancreatic cancer ( 26098869) Severe bacterial meningitis ( 31092817)
Interacting Genes		8 interacting genes: AATK EPHA2 ERBB3 IGF1R LMTK2 PTK7 ROR1 ROR2	13 interacting genes: APP DUPD1 DUSP14 DUSP18 DUSP19 DUSP21 ILKAP MFHAS1 PPM1B PPM1F PTPN6 PTPRR STYX
Entrez ID		338599	4919
HPRD ID		16846	03821
Ensembl ID		ENSG00000188716	ENSG00000185483
Uniprot IDs		Q68J44	Q01973
PDB IDs		2Y96	5Z55 6BA5 6BAN
Enriched GO Terms of Interacting Partners?
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