DUPD1 and LMTK2

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		DUPD1	LMTK2
Description		dual specificity phosphatase and pro isomerase domain containing 1	lemur tyrosine kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex	Early Endosome Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane Growth Cone Neuronal Cell Body Receptor Complex Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Protein Homodimerization Activity	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Receptor Recycling Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Endocytic Recycling Negative Regulation Of Phosphoprotein Phosphatase Activity Transferrin Transport Positive Regulation Of Kinase Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS		Anxiety disorder ( 25390645) Height ( 31562340)	Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 18264097)
Interacting Genes		8 interacting genes: AATK EPHA2 ERBB3 IGF1R LMTK2 PTK7 ROR1 ROR2	24 interacting genes: CDC14A CDC25C CDK5 CDK5R1 DUPD1 DUSP14 DUSP19 DUSP6 ILKAP MTMR6 PPM1A PPM1F PPM1K PPP1CA PPP1CB PPP1CC PPP1R2 PPP3CB PTPDC1 PTPN12 PTPN6 PTPRR STYX TPTE2
Entrez ID		338599	22853
HPRD ID		16846	13994
Ensembl ID		ENSG00000188716	ENSG00000164715
Uniprot IDs		Q68J44	Q8IWU2
PDB IDs		2Y96
Enriched GO Terms of Interacting Partners?
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