APLP1 and UTP14A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		APLP1	UTP14A
Description		amyloid beta precursor like protein 1	UTP14A small subunit processome component
Image			No pdb structure
GO Annotations	Cellular Component	Basement Membrane Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Zinc Copper
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		42 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	44 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 GADD45G HNRNPH3 HOOK2 HTT LAMTOR5 LDOC1 LSM3 NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SSR1 TERF1 TINAGL1 TP53 TP53BP2 TRDMT1 VIM WDR33 ZNF24
Entrez ID		333	10813
HPRD ID		00102	06712
Ensembl ID		ENSG00000105290	ENSG00000156697
Uniprot IDs		P51693	Q9BVJ6
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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