HSPD1 and PLCG2

  • Number of citations of the paper that reports this interaction (PubMedID 25814554)
  • 22
  • Data Source:
  • BioGRID (two hybrid)

HSPD1

PLCG2

Description heat shock protein family D (Hsp60) member 1 phospholipase C gamma 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 28714976)
  • Blood protein levels ( 30072576)
  • Breast cancer (menopausal hormone therapy interaction) ( 24080446)
  • Coronary artery disease ( 29212778)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Height ( 28552196)
  • Inflammatory bowel disease ( 28067908)
  • Mean platelet volume ( 27863252)
  • Metabolite levels ( 23823483)
  • Platelet distribution width ( 27863252)
  • Ulcerative colitis ( 28067908)
  • Upper eyelid morphology ( 29921221)
  • Venous thromboembolism ( 31420334 31676865)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 47 interacting genes: ALDH2 APP BAK1 BRCA1 CA2 CASP3 CASP9 CEP70 CLEC7A CLU DHFR ERG FAM107A FHIT H2BC21 HSPE1 ITGA3 ITGB1 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP5-9 LRRK2 LZTS2 MAPK6 MCPH1 NOS1AP NOTCH2NLA NR3C1 PLCG2 PLG PPP2R1A PPP2R1B PRKACA PRNP PTEN PTPN11 RASA1 RGS20 SAMD3 SUMO4 SUPT6H TLR1 TMCC2 TRIM63 YWHAG 50 interacting genes: ASB9 BLK BLNK BTK CBLB CD19 DAPP1 EGFR ELK1 EPOR EPYC ESD FCER1G FLT1 FYN GAB1 GAB2 GABPB2 HCK HSPD1 IRS1 ISL1 ITK JAK1 JAK2 KCTD17 KDR KHDRBS1 LAT LAT2 LCK LCP2 LHX8 LIME1 LYN NPM1 PRKD1 PTPN6 PTTG1 RALBP1 RTL10 SETD9 SH3BP2 SHC1 SYK TEC TP53 TWIST2 ZKSCAN7 ZNF512B
Entrez ID 3329 5336
HPRD ID 00318 02570
Ensembl ID ENSG00000144381 ENSG00000197943
Uniprot IDs A0A024R3X4 P10809 P16885
PDB IDs 4PJ1 2K2J 2W2W 2W2X
Enriched GO Terms of Interacting Partners?
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