HOXA10 and EMX1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HOXA10	EMX1
Description		homeobox A10	empty spiracles homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Cytoplasm	Nuclear Chromatin Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Histone Deacetylase Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Skeletal System Development Multicellular Organism Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Uterus Development	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Post-embryonic Development Cerebral Cortex Regionalization Cerebral Cortex Neuron Differentiation Neuron Differentiation Response To Drug Brain Morphogenesis Homeostasis Of Number Of Cells Radial Glial Cell Differentiation Neuroepithelial Cell Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Neuron Projection Extension
Pathways
Drugs		Calcitriol
Diseases
GWAS		Dental caries ( 23259602) Hypertension ( 31879980 30487518) Mean arterial pressure ( 30487518)	Schizophrenia ( 28991256 30285260)
Interacting Genes		12 interacting genes: CREBBP EMX1 EP300 FOXO1 GMNN MEIS1 PBX1 POLR3D PTPN6 SIRT2 SNAPC1 SPI1	8 interacting genes: ALX4 ELK1 GTF2A1L HOXA10 LINC00839 POLR2D PRDM4 TP63
Entrez ID		3206	2016
HPRD ID		00845	08963
Ensembl ID		ENSG00000253293	ENSG00000135638
Uniprot IDs		P31260	Q04741
PDB IDs
Enriched GO Terms of Interacting Partners?
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