HNRNPF and RBFOX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		HNRNPF	RBFOX2
Description		heterogeneous nuclear ribonucleoprotein F	RNA binding fox-1 homolog 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Single-stranded RNA Binding Protein Binding TBP-class Protein Binding	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Interleukin-12-mediated Signaling Pathway Regulation Of RNA Splicing	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	FGFR2 alternative splicing
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Antisaccade task score ( 31596458)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		36 interacting genes: AURKA C1orf94 CCDC33 DZIP3 EIF4ENIF1 ERG HNRNPA0 HNRNPD HNRNPH1 HNRNPH3 HNRNPM HNRNPUL1 HSFY1 HSPB1 IKZF3 NCBP1 NCBP2 NDRG1 POLR2A PRPF40A RBFOX1 RBFOX2 RBM4 SF1 SF3B4 SNRPC SUMO2 SUMO4 TFG TGM2 TLE5 TOE1 TXNL4A VAV2 YWHAQ ZNF689	53 interacting genes: APH1A ATN1 ATXN1 ATXN1L BOLL BRD7 C1orf94 CAMK2B CHAF1A CLASP2 DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH2 HNRNPK KHDRBS1 MAGED1 MAPK1IP1L MED7 NAF1 NR2E3 PCBP1 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBM22 RBM23 RBM42 RBPMS RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC SPOP TOLLIP U2AF2 VAC14 ZNF137P
Entrez ID		3185	23543
HPRD ID		03023	15231
Ensembl ID		ENSG00000169813	ENSG00000100320
Uniprot IDs		A0A024R7T3 P52597	O43251
PDB IDs		2HGL 2HGM 2HGN 2KFY 2KG0 2KG1 3TFY	2CQ3
Enriched GO Terms of Interacting Partners?
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