HLA-DPB1 and CD74

  • Number of citations of the paper that reports this interaction (PubMedID 26186194)
  • 367
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo)

HLA-DPB1

CD74

Description major histocompatibility complex, class II, DP beta 1 CD74 molecule
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
  • Anti-rubella virus IgG levels ( 30053915)
  • Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757)
  • Aspirin exacerbated respiratory disease in asthmatics ( 23180272)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 29875488)
  • Chronic hepatitis B infection ( 24940741 25802187)
  • Dermatomyositis ( 27153935)
  • EGFR mutation-positive lung adenocarcinoma ( 27501781)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Gait speed in old age ( 28077804)
  • Hepatitis B ( 21750111 19349983)
  • Hepatitis B (viral clearance) ( 22737229)
  • Hepatitis B vaccine response ( 21764829)
  • IgA nephropathy ( 25305756)
  • Monocyte count ( 27863252)
  • Myositis ( 26291516)
  • Nephropathy ( 21399633)
  • Nodular sclerosis Hodgkin lymphoma ( 29196614)
  • Plantar warts ( 28928442)
  • Primary biliary cholangitis ( 28425483)
  • Pulmonary arterial hypertension ( 30527956)
  • Response to hepatitis B vaccine ( 31243853 29534301)
  • Rosacea symptom severity ( 29771307)
  • Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
  • Severe aplastic anemia ( 32004448)
  • Sjögren's syndrome ( 24097066 28076899)
  • Susceptibility to persistent hepatitis B virus infection ( 27244555)
  • Systemic sclerosis ( 21779181)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Wegener's granulomatosis ( 23740775)
  • White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)
Interacting Genes 7 interacting genes: CD74 COPB1 HLA-DPA1 LZTS2 ROBO2 RTN4 TRIP6 16 interacting genes: APP CD1D CD44 CTSF CTSL HADHA HLA-DMA HLA-DMB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQB1 HLA-DRA LAMTOR5 MAP3K1 MIF
Entrez ID 3115 972
HPRD ID 00832 00825
Ensembl ID ENSG00000223865 ENSG00000019582
Uniprot IDs I4EC15 P04440 P04233
PDB IDs 3LQZ 4P4K 4P4R 4P57 4P5K 4P5M 1A6A 1ICF 1IIE 1L3H 1MUJ 3PDO 3PGC 3PGD 3QXA 3QXD 4AEN 4AH2 4X5W 5KSU 5KSV
Enriched GO Terms of Interacting Partners?
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