HLA-DPB1 and ROBO2

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 114
  • Data Source:
  • BioGRID (two hybrid)

HLA-DPB1

ROBO2

Description major histocompatibility complex, class II, DP beta 1 roundabout guidance receptor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
  • Anti-rubella virus IgG levels ( 30053915)
  • Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757)
  • Aspirin exacerbated respiratory disease in asthmatics ( 23180272)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 29875488)
  • Chronic hepatitis B infection ( 24940741 25802187)
  • Dermatomyositis ( 27153935)
  • EGFR mutation-positive lung adenocarcinoma ( 27501781)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Gait speed in old age ( 28077804)
  • Hepatitis B ( 21750111 19349983)
  • Hepatitis B (viral clearance) ( 22737229)
  • Hepatitis B vaccine response ( 21764829)
  • IgA nephropathy ( 25305756)
  • Monocyte count ( 27863252)
  • Myositis ( 26291516)
  • Nephropathy ( 21399633)
  • Nodular sclerosis Hodgkin lymphoma ( 29196614)
  • Plantar warts ( 28928442)
  • Primary biliary cholangitis ( 28425483)
  • Pulmonary arterial hypertension ( 30527956)
  • Response to hepatitis B vaccine ( 31243853 29534301)
  • Rosacea symptom severity ( 29771307)
  • Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
  • Severe aplastic anemia ( 32004448)
  • Sjögren's syndrome ( 24097066 28076899)
  • Susceptibility to persistent hepatitis B virus infection ( 27244555)
  • Systemic sclerosis ( 21779181)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Wegener's granulomatosis ( 23740775)
  • White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)
  • Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965)
  • Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
  • Chronotype ( 30696823)
  • Expressive vocabulary in infants ( 25226531)
  • Familial lung adenocarcinoma ( 29924316)
  • Hand grip strength ( 29691431)
  • Hip circumference ( 28552196)
  • Metabolite levels ( 23823483)
  • Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
  • Morning person ( 30696823)
  • Periodontitis (PAL4Q3) ( 24024966)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Response to ketamine in bipolar disorder or major depression (dissociation effects) ( 30552317)
  • Type 2 diabetes ( 30297969)
Interacting Genes 7 interacting genes: CD74 COPB1 HLA-DPA1 LZTS2 ROBO2 RTN4 TRIP6 16 interacting genes: BNIP3L CENPU CPE HLA-DPB1 NR1H2 NR4A1 OLFM2 PPP1R1B RDH11 ROBO1 RPS6KA5 SLIT2 SLIT3 SSRP1 TRIM13 UBQLN4
Entrez ID 3115 6092
HPRD ID 00832 11895
Ensembl ID ENSG00000223865 ENSG00000185008
Uniprot IDs I4EC15 P04440 Q9HCK4
PDB IDs 3LQZ 4P4K 4P4R 4P57 4P5K 4P5M 1UEM 1UJT 2EDJ 5NOI 6I9S 6IAA
Enriched GO Terms of Interacting Partners?
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