HLA-DOB and HLA-DMB

Number of citations of the paper that reports this interaction (PubMedID 9311912)
55

Data Source:
HPRD (in vivo)

		HLA-DOB	HLA-DMB
Description		major histocompatibility complex, class II, DO beta	major histocompatibility complex, class II, DM beta
Image
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Membrane Integral Component Of Membrane MHC Class II Protein Complex	Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex Intracellular Membrane-bounded Organelle
	Molecular Function	MHC Class II Protein Complex Binding MHC Class II Receptor Activity	Protein Binding MHC Class II Protein Complex Binding
	Biological Process	Adaptive Immune Response Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Adaptive Immune Response MHC Class II Protein Complex Assembly Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Pathways		MHC class II antigen presentation	MHC class II antigen presentation
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma and major depressive disorder ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 23266558) Kawasaki disease ( 22446962) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 30285260) Squamous cell lung carcinoma ( 28604730) Takayasu arteritis ( 25604533) Type 2 diabetes ( 30054458)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Dermatomyositis ( 27153935) Lung cancer ( 28604730) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Schizophrenia ( 30285260) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		2 interacting genes: CDKN2A HLA-DMB	11 interacting genes: CD63 CD74 CD82 CUL3 DPM2 HLA-DMA HLA-DOB HLA-DRA MDM2 PSEN2 TEAD1
Entrez ID		3112	3109
HPRD ID		08368	00831
Ensembl ID		ENSG00000241106	ENSG00000242574
Uniprot IDs		P13765 Q5QNS2	A0A1V0E3P2 P28068
PDB IDs		4I0P	1HDM 2BC4 4FQX 4GBX 4I0P
Enriched GO Terms of Interacting Partners?
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