ZBTB48 and TNFRSF14

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		ZBTB48	TNFRSF14
Description		zinc finger and BTB domain containing 48	TNF receptor superfamily member 14
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Cytosol	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding Cytokine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Transcription, DNA-templated	Adaptive Immune Response Positive Regulation Of Cytokine Secretion Involved In Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Innate Immune Response Negative Regulation Of Alpha-beta T Cell Proliferation Viral Entry Into Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of T Cell Migration
Pathways			Costimulation by the CD28 family Costimulation by the CD28 family TNFs bind their physiological receptors
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 26426971) Celiac disease ( 20190752) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory bowel disease ( 28067908) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 28445677) Primary sclerosing cholangitis ( 23603763) Rheumatoid arthritis ( 24449572 30423114 18794853 24390342 20453842) Ulcerative colitis ( 28067908 26398853 23128233 21297633)
Interacting Genes		18 interacting genes: C11orf58 CDK2AP2 CDKN1A DVL2 DVL3 EP300 GPATCH2L ILK KRTAP10-5 LLCFC1 NME7 PNRC2 RGS2 TNFRSF14 TRIM41 UPF2 ZBTB7A ZBTB8A	30 interacting genes: A2M APP BTLA CD160 CEP126 CHD3 DGKD DRAP1 DYNLL1 ESR1 HDAC3 HDAC4 IMPA2 ITFG1 LTA MBTPS1 NDUFS2 NRIP1 RAD21 SERPINA4 TNFSF13 TNFSF14 TRAF1 TRAF2 TRAF3 TRAF5 UBQLN4 VIM WDR73 ZBTB48
Entrez ID		3104	8764
HPRD ID		01316	04122
Ensembl ID		ENSG00000204859	ENSG00000157873
Uniprot IDs		A8K291 B2R702 P10074	A0A024R052 Q92956
PDB IDs		3B84 5YJ3	1JMA 2AW2 4FHQ 4RSU 5T2Q 5T2R 6NG3
Enriched GO Terms of Interacting Partners?
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