ZBTB48 and DVL3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		ZBTB48	DVL3
Description		zinc finger and BTB domain containing 48	dishevelled segment polarity protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Cytosol	Nuclear Chromatin Cytosol
	Molecular Function	Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Protease Binding Signaling Receptor Binding Frizzled Binding Protein Binding Beta-catenin Binding Rac GTPase Binding
	Biological Process	Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Transcription, DNA-templated	Positive Regulation Of Protein Phosphorylation Intracellular Signal Transduction Non-canonical Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Response To Drug Positive Regulation Of JUN Kinase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Transcription, DNA-templated Protein Stabilization Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Neuron Projection Arborization Regulation Of Cellular Protein Localization Beta-catenin Destruction Complex Disassembly
Pathways			TCF dependent signaling in response to WNT WNT mediated activation of DVL PCP/CE pathway PCP/CE pathway Degradation of DVL Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane Negative regulation of TCF-dependent signaling by DVL-interacting proteins RHO GTPases Activate Formins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS			Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Major depressive disorder ( 22472876)
Interacting Genes		18 interacting genes: C11orf58 CDK2AP2 CDKN1A DVL2 DVL3 EP300 GPATCH2L ILK KRTAP10-5 LLCFC1 NME7 PNRC2 RGS2 TNFRSF14 TRIM41 UPF2 ZBTB7A ZBTB8A	49 interacting genes: ADAP1 AXIN1 BAHD1 C8orf33 CCNK CSNK1D CSNK1E CSNK2A1 CTNNB1 DAB2 DIDO1 DPPA2 DVL1 ENKD1 FAM13C KAT7 KLF3 KLHL12 LNX1 LRRK2 LY6H MARK2 MATN2 NKD1 NOL12 NXF1 PIK3CB PITX1 PLN PPM1A PPP2CA PRPF3 PSMF1 RAB18 RPS10 RWDD2B SNX22 STOM SYT6 TNFAIP8L1 UTP3 VANGL1 WT1 YTHDC1 ZBTB48 ZNF264 ZNF408 ZNF512B ZNF697
Entrez ID		3104	1857
HPRD ID		01316	03222
Ensembl ID		ENSG00000204859	ENSG00000161202
Uniprot IDs		A8K291 B2R702 P10074	Q92997 Q9UG07
PDB IDs		3B84 5YJ3
Enriched GO Terms of Interacting Partners?
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