ZNRD1 and CIC

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNRD1	CIC
Description		zinc ribbon domain containing 1	capicua transcriptional repressor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase I Complex	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Zinc Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) HIV-1 control ( 20041166) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)	Bitter alcoholic beverage consumption ( 31046077)
Interacting Genes		17 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 UBE2I ZNF593	14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1
Entrez ID		30834	23152
HPRD ID		09601	10831
Ensembl ID		ENSG00000066379	ENSG00000079432
Uniprot IDs		Q2L6J2 Q9P1U0	A0A0A0MQR4 Q96RK0
PDB IDs			2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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