HGD and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HGD	CLDN7
Description		homogentisate 1,2-dioxygenase	claudin 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane
	Molecular Function	Homogentisate 1,2-dioxygenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Cellular Amino Acid Metabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Oxidation-reduction Process	Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Positive Regulation Of Cell Motility
Pathways		Tyrosine catabolism	Tight junction interactions
Drugs
Diseases		Alkaptonuria
GWAS			Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		4 interacting genes: CLDN7 GIT2 PCDHGC3 TERF1	7 interacting genes: AQP2 EPCAM GLP1R HGD RHOXF2 SYNE4 TJP1
Entrez ID		3081	1366
HPRD ID		06315	07633
Ensembl ID		ENSG00000113924	ENSG00000181885
Uniprot IDs		B3KW64 Q93099	A0A384ME58 F5H496 O95471
PDB IDs		1EY2 1EYB
Enriched GO Terms of Interacting Partners?
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