ERO1A and GPX8

Number of citations of the paper that reports this interaction (PubMedID 21215271)
69

Data Source:
BioGRID (protein complementation assay)

		ERO1A	GPX8
Description		endoplasmic reticulum oxidoreductase 1 alpha	glutathione peroxidase 8 (putative)
Image
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Lumen Integral Component Of Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor	Peroxidase Activity Glutathione Peroxidase Activity
	Biological Process	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Oxidation-reduction Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia	Cellular Response To Oxidative Stress Oxidation-reduction Process Cellular Oxidant Detoxification
Pathways		Insulin processing Detoxification of Reactive Oxygen Species	Detoxification of Reactive Oxygen Species
Drugs			Glutathione
Diseases
GWAS		Heel bone mineral density ( 30598549)	Cocaine dependence ( 31212010)
Interacting Genes		10 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 P4HB PDIA3 PDILT PELI2 RHOU	1 interacting genes: ERO1A
Entrez ID		30001	493869
HPRD ID		13278	17416
Ensembl ID		ENSG00000197930	ENSG00000164294
Uniprot IDs		Q96HE7	B4DPY0 E7ETY7 J3KNB5 Q8TED1
PDB IDs		3AHQ 3AHR	3CYN 3KIJ
Enriched GO Terms of Interacting Partners?
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