ERO1A and PDILT

Number of citations of the paper that reports this interaction (PubMedID 15475357)
23

Data Source:
HPRD (in vivo, in vitro)

		ERO1A	PDILT
Description		endoplasmic reticulum oxidoreductase 1 alpha	protein disulfide isomerase like, testis expressed
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GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle	Cell Endoplasmic Reticulum
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor	Protein Disulfide Isomerase Activity
	Biological Process	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Oxidation-reduction Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia	Protein Folding Multicellular Organism Development Spermatid Development Cell Migration Cell Redox Homeostasis
Pathways		Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)	Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 29273807) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462 29403010) Diastolic blood pressure ( 27841878) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Kidney function decline traits ( 25493955) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (diuretics) ( 31015401) Urate levels ( 31578528) Urinary uromodulin levels ( 24578125) Urolithiasis ( 30975718)
Interacting Genes		10 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 P4HB PDIA3 PDILT PELI2 RHOU	1 interacting genes: ERO1A
Entrez ID		30001	204474
HPRD ID		13278	15111
Ensembl ID		ENSG00000197930	ENSG00000169340
Uniprot IDs		Q96HE7	Q8N807
PDB IDs		3AHQ 3AHR	4NWY 5XF7
Enriched GO Terms of Interacting Partners?
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