TRIM59 and OTOL1

		TRIM59	OTOL1
Description		tripartite motif containing 59	otolin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B	Extracellular Region Collagen Trimer Extracellular Space Extracellular Matrix
	Molecular Function	Protein Binding Zinc Ion Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding
	Biological Process	Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response	Extracellular Matrix Organization Otolith Mineralization Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Intrinsic epigenetic age acceleration ( 29374233) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Adventurousness ( 30643258) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Aging (time to death) ( 21782286) Alcohol consumption (drinks per week) ( 30643258) Hepcidin/ferritin ratio ( 27846281) Schizophrenia ( 28991256 30285260) Type 2 diabetes ( 30130595)
Interacting Genes		9 interacting genes: ECSIT ESR1 ESR2 NRM OTOL1 PPM1L RHOU VTI1B ZDHHC22	1 interacting genes: TRIM59
Entrez ID		286827	131149
HPRD ID		15568	19083
Ensembl ID		ENSG00000213186	ENSG00000182447
Uniprot IDs		Q8IWR1	A6NHN0
PDB IDs
Enriched GO Terms of Interacting Partners?
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