CXCL9 and SFTPC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CXCL9	SFTPC
Description		C-X-C motif chemokine ligand 9	surfactant protein C
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell External Side Of Plasma Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Multivesicular Body Lumen
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Protein Binding Identical Protein Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Leukocyte Chemotaxis Regulation Of Cell Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion	Respiratory Gaseous Exchange Cellular Protein Metabolic Process
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Surfactant metabolism Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Blood protein levels ( 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		10 interacting genes: BMF CCR3 CXCR3 DPP4 FBXO7 KASH5 PAX8 PTPN5 SFTPC SYNE4	12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2
Entrez ID		4283	6440
HPRD ID		03416	01520
Ensembl ID		ENSG00000138755	ENSG00000168484
Uniprot IDs		Q07325	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?