OPLAH and GK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		OPLAH	GK
Description		5-oxoprolinase, ATP-hydrolysing	glycerol kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Mitochondrion Mitochondrial Outer Membrane Cytosol Extracellular Exosome
	Molecular Function	ATP Binding 5-oxoprolinase (ATP-hydrolyzing) Activity	Glycerol Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor
	Biological Process	Glutathione Metabolic Process Glutathione Biosynthetic Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glycerol-3-phosphate Biosynthetic Process
Pathways		Glutathione synthesis and recycling Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)	Triglyceride biosynthesis
Drugs		Glutamic Acid
Diseases			Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Blood metabolite levels ( 24816252) Metabolic traits ( 21886157) Serum metabolite levels ( 23093944)	Cardiovascular risk factors (age interaction) ( 20838585)
Interacting Genes		1 interacting genes: GK	11 interacting genes: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA
Entrez ID		26873	2710
HPRD ID		14880	08363
Ensembl ID		ENSG00000178814	ENSG00000198814
Uniprot IDs		O14841	B4DH54 P32189
PDB IDs
Enriched GO Terms of Interacting Partners?
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