GK and AOX1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GK	AOX1
Description		glycerol kinase	aldehyde oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Extracellular Exosome	Cytosol Extracellular Exosome
	Molecular Function	Glycerol Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor	Aldehyde Oxidase Activity Xanthine Dehydrogenase Activity Iron Ion Binding Electron Transfer Activity Identical Protein Binding Protein Homodimerization Activity Molybdopterin Cofactor Binding Flavin Adenine Dinucleotide Binding NAD Binding 2 Iron, 2 Sulfur Cluster Binding FAD Binding Geranial:oxygen Oxidoreductase Activity Heptaldehyde:oxygen Oxidoreductase Activity
	Biological Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glycerol-3-phosphate Biosynthetic Process	Xanthine Catabolic Process Drug Metabolic Process Electron Transport Chain Vitamin B6 Metabolic Process Oxidation-reduction Process
Pathways		Triglyceride biosynthesis	Vitamins B6 activation to pyridoxal phosphate
Drugs			Eniluracil
Diseases		Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)	Xanthinuria
GWAS		Cardiovascular risk factors (age interaction) ( 20838585)	Hip circumference adjusted for BMI ( 28552196) Intelligence ( 22449649) Late-onset Alzheimer's disease ( 27770636)
Interacting Genes		11 interacting genes: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA	7 interacting genes: ABCA1 BCS1L CRKL ERRFI1 GK RBL1 RCHY1
Entrez ID		2710	316
HPRD ID		08363	07537
Ensembl ID		ENSG00000198814	ENSG00000138356
Uniprot IDs		B4DH54 P32189	Q06278
PDB IDs			4UHW 4UHX 5EPG 6Q6Q
Enriched GO Terms of Interacting Partners?
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