BSCL2 and USE1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BSCL2	USE1
Description		BSCL2 lipid droplet biogenesis associated, seipin	unconventional SNARE in the ER 1
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle SNARE Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Lysosomal Transport Protein Transport Protein Catabolic Process Secretion By Cell
Pathways			COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases		Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS		Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Night sleep phenotypes ( 27126917)
Interacting Genes		8 interacting genes: CPEB2 NSG1 PLEKHF2 PLIN1 SMIM3 SMLR1 TMEM19 USE1	6 interacting genes: APP BSCL2 CREB3 LMNA MEOX2 TRIM27
Entrez ID		26580	55850
HPRD ID		05858	11299
Ensembl ID		ENSG00000168000	ENSG00000053501
Uniprot IDs		A0A024R540 A0A024R549 Q96G97	Q9NZ43
PDB IDs		6DS5
Enriched GO Terms of Interacting Partners?
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