PTPN18 and PSTPIP1

Number of citations of the paper that reports this interaction (PubMedID 11971877)
79

Data Source:
HPRD (in vivo)

		PTPN18	PSTPIP1
Description		protein tyrosine phosphatase non-receptor type 18	proline-serine-threonine phosphatase interacting protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Blastocyst Formation Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation ERBB2 Signaling Pathway Cellular Response To Cytokine Stimulus Negative Regulation Of ERBB Signaling Pathway	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response
Pathways		Downregulation of ERBB2 signaling Interleukin-37 signaling	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS			Neurofibrillary tangles ( 31497858)
Interacting Genes		11 interacting genes: AATK ABL1 ARHGAP5 CSK EGFR ERBB2 GAB1 PSTPIP1 PSTPIP2 SRC TEC	42 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 DNM2 EXOC5 FAM90A1 FASLG FBXL18 HMG20A KHDRBS1 LSM4 MEFV MFGE8 MVP NAV2 PCDHB14 PRPF31 PTPN12 PTPN18 RINT1 RTP5 RXRB SDCBP SH2D4A SHBG SPG7 SYCE1 TFIP11 TRAF3IP3 TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175 ZNF688
Entrez ID		26469	9051
HPRD ID		05961	05891
Ensembl ID		ENSG00000072135	ENSG00000140368
Uniprot IDs		Q99952	A0A0S2Z5P3 O43586
PDB IDs		2OC3 4GFU 4GFV 4NND	2DIL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?