GBP2 and HSPE1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GBP2	HSPE1
Description		guanylate binding protein 2	heat shock protein family E (Hsp10) member 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Actin Cytoskeleton Symbiont-containing Vacuole Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Homodimerization Activity	RNA Binding Protein Binding ATP Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Osteoblast Differentiation Protein Folding Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding
Pathways		Interferon gamma signaling Interferon alpha/beta signaling
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		22 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG	14 interacting genes: ALDH2 APLP1 CASP3 CRMP1 EEF1A1 ERG28 GBP2 HSPD1 LRIF1 SAT1 STK3 TLE1 UNC119 ZHX1
Entrez ID		2634	3336
HPRD ID		02682	02535
Ensembl ID		ENSG00000162645	ENSG00000115541
Uniprot IDs		P32456 Q8TCE5	A0A384N6A4 P61604
PDB IDs			4PJ1
Enriched GO Terms of Interacting Partners?
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