GBP2 and SEPHS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GBP2	SEPHS1
Description		guanylate binding protein 2	selenophosphate synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Actin Cytoskeleton Symbiont-containing Vacuole Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane Nuclear Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Homodimerization Activity	Selenide, Water Dikinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding
	Biological Process	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Cellular Protein Modification Process Selenocysteine Biosynthetic Process Phosphorylation
Pathways		Interferon gamma signaling Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483)
Interacting Genes		22 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG	12 interacting genes: CDCA4 CRMP1 DEPDC7 ERG28 GBP2 IGSF21 QRICH1 SAT1 SLC35F6 SPACA9 UNC119 ZBTB25
Entrez ID		2634	22929
HPRD ID		02682	02944
Ensembl ID		ENSG00000162645	ENSG00000086475
Uniprot IDs		P32456 Q8TCE5	P49903
PDB IDs			3FD5 3FD6
Enriched GO Terms of Interacting Partners?
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