STAP1 and RETREG3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STAP1	RETREG3
Description		signal transducing adaptor family member 1	reticulophagy regulator family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Protein-containing Complex Intracellular Membrane-bounded Organelle	Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Phosphotyrosine Residue Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity SH3/SH2 Adaptor Activity Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Phospholipid Binding Protein Kinase Binding	Protein Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Macrophage Chemotaxis Negative Regulation Of Phosphorylation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Cellular Response To Lipopolysaccharide Negative Regulation Of Ruffle Assembly Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Microglial Cell Activation Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity Negative Regulation Of Microglial Cell Migration Positive Regulation Of Microglial Cell Mediated Cytotoxicity Positive Regulation Of Actin Cytoskeleton Reorganization	Positive Regulation Of Neuron Projection Development
Pathways
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		6 interacting genes: KIT PTK2B RETREG3 SH3KBP1 TEC URI1	9 interacting genes: ABHD16A ARHGAP27 ARL6IP1 GABARAPL1 KANSL1 MAP1LC3A RUNDC1 SPPL2C STAP1
Entrez ID		26228	162427
HPRD ID		16053	14108
Ensembl ID		ENSG00000035720	ENSG00000141699
Uniprot IDs		A0A024RD91 Q9ULZ2	K7EQI9 Q86VR2
PDB IDs		1X1F 3MAZ
Enriched GO Terms of Interacting Partners?
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