RETREG3 and STAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RETREG3	STAP1
Description		reticulophagy regulator family member 3	signal transducing adaptor family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Protein-containing Complex	Nucleus Nucleoplasm Cytoplasm Mitochondrion Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Phosphotyrosine Residue Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity SH3/SH2 Adaptor Activity Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Phospholipid Binding Protein Kinase Binding
	Biological Process	Positive Regulation Of Neuron Projection Development	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Macrophage Chemotaxis Negative Regulation Of Phosphorylation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Cellular Response To Lipopolysaccharide Negative Regulation Of Ruffle Assembly Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Microglial Cell Activation Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity Negative Regulation Of Microglial Cell Migration Positive Regulation Of Microglial Cell Mediated Cytotoxicity Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Drugs
Diseases
GWAS		Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Regular attendance at a pub or social club ( 29970889)
Interacting Genes		9 interacting genes: ABHD16A ARHGAP27 ARL6IP1 GABARAPL1 KANSL1 MAP1LC3A RUNDC1 SPPL2C STAP1	6 interacting genes: KIT PTK2B RETREG3 SH3KBP1 TEC URI1
Entrez ID		162427	26228
HPRD ID		14108	16053
Ensembl ID		ENSG00000141699	ENSG00000035720
Uniprot IDs		K7EQI9 Q86VR2	A0A024RD91 Q9ULZ2
PDB IDs			1X1F 3MAZ
Enriched GO Terms of Interacting Partners?
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