GAD2 and MAL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GAD2	MAL2
Description		glutamate decarboxylase 2	mal, T cell differentiation protein 2 (gene/pseudogene)
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Cell Junction Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Neurotransmitter Secretion Neurotransmitter Biosynthetic Process Response To Drug	Myelination Transcytosis
Pathways		GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs		Pyridoxal Phosphate Glutamic Acid
Diseases
GWAS		Lean body mass ( 28552196)	Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)
Interacting Genes		9 interacting genes: AGTRAP ARL6IP1 CMTM5 F10 GAD1 MAL2 PRKACA PRKCE TMEM159	21 interacting genes: ABCG8 ARFIP2 CREB3 FAM3A GAD1 GAD2 NDRG4 PBX3 PIMREG PPP1CA PTPN9 RAB37 S100B SH3GL1 SHMT2 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2
Entrez ID		2572	114569
HPRD ID		11817	14351
Ensembl ID		ENSG00000136750	ENSG00000147676
Uniprot IDs		Q05329 Q5VZ30	A0A024R9E4 Q969L2
PDB IDs		1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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