DEFB116 and POFUT1

		DEFB116	POFUT1
Description		defensin beta 116	protein O-fucosyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Endoplasmic Reticulum Membrane
	Molecular Function		Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Defense Response To Bacterium Innate Immune Response	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation
Pathways		Beta defensins Defensins	Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		Prudent dietary pattern ( 28644415) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes		1 interacting genes: POFUT1	13 interacting genes: AKT2 DEFB115 DEFB116 DLL1 DUSP15 ERGIC3 ID1 JAG1 NAP1L2 NOTCH1 PTPRA USH2A ZIC3
Entrez ID		245930	23509
HPRD ID		19020	06319
Ensembl ID		ENSG00000215545	ENSG00000101346
Uniprot IDs		Q30KQ4	Q9H488
PDB IDs			5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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