POFUT1 and DEFB116

		POFUT1	DEFB116
Description		protein O-fucosyltransferase 1	defensin beta 116
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Extracellular Region
	Molecular Function	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation	Defense Response To Bacterium Innate Immune Response
Pathways		Pre-NOTCH Processing in the Endoplasmic Reticulum	Beta defensins Defensins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)	Prudent dietary pattern ( 28644415) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		13 interacting genes: AKT2 DEFB115 DEFB116 DLL1 DUSP15 ERGIC3 ID1 JAG1 NAP1L2 NOTCH1 PTPRA USH2A ZIC3	1 interacting genes: POFUT1
Entrez ID		23509	245930
HPRD ID		06319	19020
Ensembl ID		ENSG00000101346	ENSG00000215545
Uniprot IDs		Q9H488	Q30KQ4
PDB IDs		5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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