SF3B3 and NUTF2

		SF3B3	NUTF2
Description		splicing factor 3b subunit 3	nuclear transport factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytosol Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding	Protein Binding Ran GTPase Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus MRNA Transport Protein Localization To Nuclear Pore Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs		Quercetin
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321)	Schizophrenia ( 25056061 29483656)
Interacting Genes		29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579	13 interacting genes: CANX GLRX2 KPNB1 LUC7L2 NFAT5 NUP153 NUP54 NUP62 PTMA RAN SF3B3 TERF2 WWP2
Entrez ID		23450	10204
HPRD ID		12027	12050
Ensembl ID		ENSG00000189091	ENSG00000102898
Uniprot IDs		A8K6V3 Q15393	A0A024R6Y2 P61970
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9	1GY5
Enriched GO Terms of Interacting Partners?
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