SF3B3

Description		splicing factor 3b subunit 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs		Quercetin
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		23450
HPRD ID		12027
Ensembl ID		ENSG00000189091
Uniprot IDs		A8K6V3 Q15393
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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