ITGB3BP and DDX24

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ITGB3BP	DDX24
Description		integrin subunit beta 3 binding protein	DEAD-box helicase 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Nucleolus Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding	RNA Binding RNA Helicase Activity ATP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Cell Division	RNA Metabolic Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		22 interacting genes: ACTN2 APP ARFIP2 CCNA2 CERT1 DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 LRRK2 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7	33 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTPN23 RAE1 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I VDAC3
Entrez ID		23421	57062
HPRD ID		09267	05860
Ensembl ID		ENSG00000142856	ENSG00000089737
Uniprot IDs		D3DQ59 Q13352	Q9GZR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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