ITGB3BP and UBR7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ITGB3BP	UBR7
Description		integrin subunit beta 3 binding protein	ubiquitin protein ligase E3 component n-recognin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Cytoplasm
	Molecular Function	Protein Binding Protein C-terminus Binding	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Cell Division	Biological_process Protein Ubiquitination
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		22 interacting genes: ACTN2 APP ARFIP2 CCNA2 CERT1 DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 LRRK2 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7	5 interacting genes: H2BC3 H3C15 ITGB3BP UBE2E1 UBQLN4
Entrez ID		23421	55148
HPRD ID		09267	16602
Ensembl ID		ENSG00000142856	ENSG00000012963
Uniprot IDs		D3DQ59 Q13352	Q8N806
PDB IDs
Enriched GO Terms of Interacting Partners?
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