SCFD1 and HECTD1

		SCFD1	HECTD1
Description		sec1 family domain containing 1	HECT domain E3 ubiquitin protein ligase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Cytosol Plasma Membrane Golgi Cisterna Membrane
	Molecular Function	Protein Binding Syntaxin Binding Protein-containing Complex Binding Protein N-terminus Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Response To Hypoxia Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Response To Toxic Substance Protein Transport COPII Vesicle Coating Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Toxin Transport Negative Regulation Of Autophagosome Assembly	Heart Valve Development Ventricular Septum Development Aorta Development Anatomical Structure Development Protein K63-linked Ubiquitination
Pathways		COPII-mediated vesicle transport	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793 27455348) Cognitive decline (age-related) ( 28078323) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		6 interacting genes: DLST HECTD1 PPBP STX5 USO1 USP22	10 interacting genes: HRAS HSPB1 IGSF1 KHNYN MTNR1B SCFD1 UBE2D2 UBE2D3 UBE2L3 YWHAG
Entrez ID		23256	25831
HPRD ID		10210	17098
Ensembl ID		ENSG00000092108	ENSG00000092148
Uniprot IDs		B7Z5N7 B7Z738 Q8WVM8	Q9ULT8
PDB IDs			2DK3 2LC3 3DKM
Enriched GO Terms of Interacting Partners?
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