MYCBP2 and FBXO45

Number of citations of the paper that reports this interaction (PubMedID 27173435)
49

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		MYCBP2	FBXO45
Description		MYC binding protein 2	F-box protein 45
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle	Postsynaptic Density SCF Ubiquitin Ligase Complex Cell Junction Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Ran GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance	Neuron Migration Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Tangential Migration Corticospinal Tract Morphogenesis Anterior Commissure Morphogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Synapse Assembly Involved In Innervation
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738) Multiple sclerosis ( 31604244) Vitiligo ( 27723757)
Interacting Genes		20 interacting genes: ATP13A2 ATP1B3 CALM1 CDC14B COMMD6 DACH1 EDNRB FBXL3 FBXO45 MAST3 MYC NMNAT2 PTPN12 SCEL SRPK2 UBE2D2 UBE2D3 UBE2L3 YWHAG YWHAQ	3 interacting genes: MYCBP2 PRNP TP73
Entrez ID		23077	200933
HPRD ID		10104	19508
Ensembl ID		ENSG00000005810	ENSG00000174013
Uniprot IDs		O75592	P0C2W1
PDB IDs		5O6C
Enriched GO Terms of Interacting Partners?
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