HECW1 and GFI1B

  • Number of citations of the paper that reports this interaction (PubMedID 16713569)
  • 313

HECW1

GFI1B

Description HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 growth factor independent 1B transcriptional repressor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil percentage of white cells ( 27863252)
  • Cardiometabolic and hematological traits ( 27668658)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Granulocyte count ( 27863252)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Immature fraction of reticulocytes ( 27863252)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mean corpuscular volume ( 27863252)
  • Mean platelet volume ( 27863252)
  • Myeloid white cell count ( 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
  • Platelet count ( 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Red cell distribution width ( 27863252 28957414)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Sum eosinophil basophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • White blood cell count ( 27863252)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 15 interacting genes: CACNA1A DVL1 GFI1B SCNN1A SCNN1B SSR4 TNK2 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2J2 UBE2L3 USP7 71 interacting genes: ACTN1 AGRN AJUBA ANKS3 ATXN2 BABAM2 BECN1 BEGAIN BEND5 BRCA1 CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GPAT4 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TLE5 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3
Entrez ID 23072 8328
HPRD ID 11385 05088
Ensembl ID ENSG00000002746 ENSG00000165702
Uniprot IDs Q76N89 A0A024R8F3 Q5VTD9
PDB IDs 3L4H
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?