SMG1 and UPF3A

Number of citations of the paper that reports this interaction (PubMedID 11544179)
138

Data Source:
HPRD (in vivo)

		SMG1	UPF3A
Description		SMG1 nonsense mediated mRNA decay associated PI3K related kinase	UPF3A regulator of nonsense mediated mRNA decay
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Exon-exon Junction Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Telomeric DNA Binding Metal Ion Binding	RNA Binding Protein Binding Structural Constituent Of Nuclear Pore Telomeric DNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay DNA Repair MRNA Export From Nucleus Peptidyl-serine Phosphorylation Regulation Of Telomere Maintenance Protein Autophosphorylation Phosphatidylinositol Phosphorylation Regulation Of Response To DNA Damage Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleocytoplasmic Transport Positive Regulation Of Translation MRNA Transport
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Health literacy ( 31250787) Heel bone mineral density ( 30598549)	Height ( 31562340) Nodular sclerosis Hodgkin lymphoma ( 29196614) Pulse pressure ( 30578418)
Interacting Genes		9 interacting genes: CDH5 ELOB PRKCI SMAD9 SMG5 SMG8 UPF1 UPF2 UPF3A	9 interacting genes: ALYREF APP GSK3B IFITM2 NXF1 PIGT RBM8A SMG1 UPF1
Entrez ID		23049	65110
HPRD ID		06123	09274
Ensembl ID		ENSG00000157106	ENSG00000169062
Uniprot IDs		Q96Q15	B3KUE7 Q9H1J1
PDB IDs			2L08
Enriched GO Terms of Interacting Partners?
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