TNIK and TIAM2

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 168
  • Data Source:
  • BioGRID (two hybrid)

TNIK

TIAM2

Description TRAF2 and NCK interacting kinase TIAM Rac1 associated GEF 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 28334814)
  • Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Change in serum metabolite levels ( 31636271)
  • Change in serum metabolite levels (CMS) ( 31636271)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136)
  • Frontotemporal dementia (age at onset) ( 29724592)
  • Hip circumference adjusted for BMI ( 28552196)
  • LDL cholesterol ( 21347282)
  • Lymphocyte counts ( 27863252)
  • Night sleep phenotypes ( 27126917)
  • Response to antipsychotic treatment in schizophrenia ( 29503163)
  • Type 2 diabetes ( 30054458)
  • Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
  • Asthma ( 31361310)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
  • Heel bone mineral density ( 30598549)
  • Lipoprotein (a) levels ( 26377243)
  • Triiodothyronine levels and thyroxine levels ( 30843173)
Interacting Genes 37 interacting genes: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS1 MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SMARCE1 SMURF1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1 9 interacting genes: ANXA7 DISC1 DNM2 H2AX PARD3 SH3GL2 TK1 TNIK UFD1
Entrez ID 23043 26230
HPRD ID 18206 05273
Ensembl ID ENSG00000154310 ENSG00000146426
Uniprot IDs Q9UKE5 B3KW11 Q8IVF5
PDB IDs 2X7F 5AX9 5CWZ 5D7A 6RA7
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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