TNIK and CNKSR2

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 168
  • Data Source:
  • BioGRID (two hybrid)

TNIK

CNKSR2

Description TRAF2 and NCK interacting kinase connector enhancer of kinase suppressor of Ras 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 28334814)
  • Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Change in serum metabolite levels ( 31636271)
  • Change in serum metabolite levels (CMS) ( 31636271)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136)
  • Frontotemporal dementia (age at onset) ( 29724592)
  • Hip circumference adjusted for BMI ( 28552196)
  • LDL cholesterol ( 21347282)
  • Lymphocyte counts ( 27863252)
  • Night sleep phenotypes ( 27126917)
  • Response to antipsychotic treatment in schizophrenia ( 29503163)
  • Type 2 diabetes ( 30054458)
Interacting Genes 37 interacting genes: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS1 MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SMARCE1 SMURF1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1 13 interacting genes: DLG1 DLG2 DLG3 DLG4 LRRC7 PATJ RALA RGS3 SHANK3 SMURF2 SNTA1 TJP1 TNIK
Entrez ID 23043 22866
HPRD ID 18206 06473
Ensembl ID ENSG00000154310 ENSG00000149970
Uniprot IDs Q9UKE5 A0A2R8Y622 A0A2R8Y700 A0A2R8Y7A1 A0A2U3TZH5 B3KPN2 Q8WXI2
PDB IDs 2X7F 5AX9 5CWZ 5D7A 6RA7 2EAN 3BS5
Enriched GO Terms of Interacting Partners?
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