SORCS3 and NGF

  • Number of citations of the paper that reports this interaction (PubMedID 15710408)
  • 10
  • Data Source:
  • HPRD (in vitro)

SORCS3

NGF

Description sortilin related VPS10 domain containing receptor 3 nerve growth factor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 30478444)
  • Cognitive ability ( 29186694)
  • Cognitive ability (MTAG) ( 29186694)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Depression ( 29700475)
  • Diabetic kidney disease ( 26305897)
  • Diastolic blood pressure ( 30224653)
  • Feeling miserable ( 29500382)
  • General factor of neuroticism ( 30867560)
  • General risk tolerance (MTAG) ( 30643258)
  • Intelligence (MTAG) ( 29326435)
  • Major depressive disorder ( 27479909)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Metabolite levels ( 23823483)
  • Mood instability ( 31168069)
  • Multisite chronic pain ( 31194737)
  • Non-alcoholic fatty liver disease activity score ( 31311600)
  • Rosacea symptom severity ( 29771307)
  • Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775)
  • Systolic blood pressure ( 30578418)
Interacting Genes 2 interacting genes: IDE NGF 8 interacting genes: A2M CRYAB MMP7 NGFR NTRK1 PLG SORCS3 SORT1
Entrez ID 22986 4803
HPRD ID 12100 08874
Ensembl ID ENSG00000156395 ENSG00000134259
Uniprot IDs Q86XB2 Q9UPU3 A0A346FYQ1 P01138
PDB IDs 1SG1 1WWW 2IFG 4EDW 4EDX 4ZBN 5JZ7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?