FHL2 and ZNF417

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FHL2	ZNF417
Description		four and a half LIM domains 2	zinc finger protein 417
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Focal Adhesion Z Disc M Band	Nucleus
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding Metal Ion Binding Androgen Receptor Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Response To Hormone Regulation Of Lipid Metabolic Process Androgen Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression	Generic Transcription Pathway
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Household income (MTAG) ( 31844048) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 30224653 30578418)	Depression in smokers ( 30219690)
Interacting Genes		98 interacting genes: ADAM17 AK1 APP AR ARHGAP9 ATXN1 BANP BIN1 BLZF1 BMPR2 BRCA1 CAPN1 CARD8 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DCP1A DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EP300 ESR1 FHL1 FHL3 FHL5 FOXO1 GLYR1 GNG12 HAND1 HCK HSPB2 ID3 IDH1 IER3 IGFBP5 IKZF4 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 MCM7 MDM2 MYBPC1 NIBAN1 NRF1 PFKM PHB2 PSEN2 PUF60 RAI2 REL REV1 RFX3 RUNX2 SAP30BP SAXO1 SFPQ SIGLEC6 SLC34A1 SMAD2 SMAD3 SMAD4 SP2 SRF STAT3 SUMO1P1 TNFRSF11A TRAF6 TRIM55 TRIM63 TTN WT1 ZBTB16 ZBTB25 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF212 ZNF3 ZNF331 ZNF408 ZNF417 ZNF626 ZNF638	68 interacting genes: ADAMTSL4 BEGAIN BEND5 CARD9 CCDC136 CCDC57 CCDC85B CCNDBP1 CEP44 CEP70 CEP72 CSRNP1 EFS FHL2 FHL3 FSD2 GOLGA2 HMBOX1 IKZF1 KLC3 KRT15 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LURAP1 LZTS2 MDFI MEOX2 MID2 MTUS2 NDEL1 NINL NOTCH2NLA PHC2 PLSCR1 PNMA2 PRPF31 REL RPGRIP1 RUNDC3A SPRY2 SSX2IP STX11 TCF4 TFIP11 TMCC2 TNS2 TRAF1 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSGA10 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZNF587
Entrez ID		2274	147687
HPRD ID		04026	18341
Ensembl ID		ENSG00000115641	ENSG00000173480
Uniprot IDs		Q14192 Q2XQU9 Q6I9R8	M0R230 Q8TAU3
PDB IDs		1X4K 1X4L 2D8Z 2MIU
Enriched GO Terms of Interacting Partners?
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